4-Hydroxy-2-methyl phenyl boronic acid - Names and Identifiers
4-Hydroxy-2-methyl phenyl boronic acid - Physico-chemical Properties
Molecular Formula | C7H9BO3
|
Molar Mass | 151.96 |
Density | 1.26±0.1 g/cm3(Predicted) |
Melting Point | 100-104°C |
Boling Point | 361.4±52.0 °C(Predicted) |
Flash Point | 172.4°C |
Vapor Presure | 7.43E-06mmHg at 25°C |
pKa | 9.17±0.58(Predicted) |
Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
Refractive Index | 1.569 |
4-Hydroxy-2-methyl phenyl boronic acid - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin.
R41 - Risk of serious damage to eyes
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S39 - Wear eye / face protection.
|
Hazard Class | IRRITANT |
4-Hydroxy-2-methyl phenyl boronic acid - Introduction
4-Hydroxy-2-methyl phenyl boronic acid is an organic boron compound with the chemical formula C7H9BO3.
Nature:
-Appearance: White crystalline solid
-Solubility: Soluble in alcohols and some organic solvents, slightly soluble in water
-melting point: about 170-173 ℃
Use:
-It is an important derivative of aromatic compounds and is often used as an intermediate in organic synthesis.
-Due to its reactivity with other compounds, it can be used to synthesize anti-cancer drugs, pesticides, photosensitive materials and coordination compounds.
Preparation Method:
4-Hydroxy-2-methyl phenyl boronic acid has various preparation methods, and the common ones are as follows:
-can be obtained by the hydroxyl etherification reaction of p-methylphenylboronic acid. The specific reaction steps include reacting methylbenzeneboronic acid with hydroquinone under alkaline conditions to produce 4-Hydroxy-2-methyl phenyl boronic acid.
-It can also be obtained by the alkylation reaction of p-methylphenylboronic acid. The specific reaction steps include reacting methylphenylboronic acid with iodane under alkaline conditions to produce 4-Hydroxy-2-methylphenyl boronic acid.
Safety Information:
4-Hydroxy-2-methyl phenyl boronic acid is a relatively safe compound under general use conditions, but the following matters still need to be paid attention:
-During use, wear protective gloves and protective glasses to prevent contact with skin and eyes.
-Avoid inhaling its dust or gas and avoid ingestion.
-During storage, it is necessary to keep dry and avoid contact with oxidants and other substances.
-In case of swallowing, entering eyes or skin contact, rinse immediately with water and seek medical help.
Last Update:2024-04-09 15:17:58